Structure of PDB 5j89 Chain A

Receptor sequence
>5j89A (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQF
VHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMIS
YGGADYKRITVKVNAPYAAALEHHHHH
3D structure
PDB5j89 Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6GX A T20 Y56 M115 A121 D122 Y123 T3 Y39 M98 A104 D105 Y106 BindingDB: IC50=18nM,EC50=>10000nM
External links
PDB RCSB:5j89, PDBe:5j89, PDBj:5j89
PDBsum5j89
PubMed27083005
UniProtQ9NZQ7|PD1L1_HUMAN Programmed cell death 1 ligand 1 (Gene Name=CD274)

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