Structure of PDB 5j6f Chain A

Receptor sequence
>5j6fA (length=352) Species: 1233873 (Geobacillus sp. GHH01) [Search protein sequence]
NERLDELRARVDEINLQLLKLINERGRLVQEIGKIKEAQGTHRYDPVRER
KMLDLISEHNDGPFETSTLQHIFKEIFKAALELQEDDHRKALLVSRKKHP
ENTIVEVKGERIGDGNQYFVMGPCAVESYEQVAAVAEAVKKQGIKLLRGG
AYKPRTSPYDFQGLGVEGLKILKRIADEFDLAVISEIVTPADIEIALDYI
DVIQIGARNMQNFELLKAAGQVNKPILLKRGLAATIEEFINAAEYIMSQG
NGQIILCERGIRTYERATRNTLDISAVPILKKETHLPVFVDVTHSTGRRD
LLIPCAKAALAIGADGVMAEVHPDPAVALSDSAQQMDIAQFNEFMEEVRA
FQ
3D structure
PDB5j6f Interdomain Conformational Changes Provide Allosteric Regulation en Route to Chorismate.
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
5.4.99.5: chorismate mutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A C126 H296 E322 D333 C124 H294 E320 D331
BS02 PRE A R27 I34 K38 Y46 D47 R50 M54 R25 I32 K36 Y44 D45 R48 M52
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0004106 chorismate mutase activity
GO:0016740 transferase activity
GO:0016832 aldehyde-lyase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0046417 chorismate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5j6f, PDBe:5j6f, PDBj:5j6f
PDBsum5j6f
PubMed27502275
UniProtL8A208

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