Structure of PDB 5j5p Chain A

Receptor sequence
>5j5pA (length=397) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
KEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHLVWEIVDNAV
DEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTILH
AGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGG
KPVTTLKKIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFL
LKNVTLSLTDKRTDEAIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDN
GFQVEVALQYNDGFSDNILSFVNNVRTKDGGTHETGLKSAITKVMNDYAR
KTGLLKEKDKNLEGSDYREGLAAVLSILVPEEHLQFEGQTKDKLGSPLAR
PVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAARKARDESR
3D structure
PDB5j5p Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase.
ChainA
Resolution1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T288 S292 T295 K296 N299 N314 K346 T285 S289 T292 K293 N296 N311 K343
BS02 ANP A N51 E55 M83 I98 G105 G106 K107 Y113 G118 L119 H120 G121 V122 G123 S124 T172 K344 N48 E52 M80 I95 G102 G103 K104 Y110 G115 L116 H117 G118 V119 G120 S121 T169 K341
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:5j5p, PDBe:5j5p, PDBj:5j5p
PDBsum5j5p
PubMed29968711
UniProtQ59961|PARE_STRPN DNA topoisomerase 4 subunit B (Gene Name=parE)

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