Structure of PDB 5j48 Chain A

Receptor sequence
>5j48A (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
GSTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQ
GARGDTFFIISKGTVNVTREDDPVFLRTLGKGDWFGEKALQGEDVRTANV
IAAEAVTCLVIDRDSFKHLIGGLDDVSNKAY
3D structure
PDB5j48 Structural Basis of Analog Specificity in PKG I and II.
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.12: cGMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6FW A V283 L296 R297 W304 F305 G306 E307 K308 A309 R316 T317 A318 Y351 V67 L76 R77 W84 F85 G86 E87 K88 A89 R96 T97 A98 Y131
Gene Ontology
Molecular Function
GO:0004692 cGMP-dependent protein kinase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:5j48, PDBe:5j48, PDBj:5j48
PDBsum5j48
PubMed28793191
UniProtQ13976|KGP1_HUMAN cGMP-dependent protein kinase 1 (Gene Name=PRKG1)

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