Structure of PDB 5j3u Chain A

Receptor sequence
>5j3uA (length=261) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
VYEKDEGQKEQLERILRQSFLFNSLDEKDLNTVILAMQEKKIEASTCLIR
EGDDGECLYIVQSGELNCSKLIDGEERVVKVVGPGDAFGELALLYNAPRA
ATVTSVSACDLWELGRDTFNAIVKDAATKRRSMYDSFLKSVHILDGMDAY
ERGKVADALRTEMFTDGAYIVRQGELGDVFYIVEEGSAVATKSFGPGQPP
IEVKKYQAGDYFGELALINEEPRAANVIAHGICKVACLERKSFKRLMGSV
QDLLSKKASEY
3D structure
PDB5j3u Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.12: cGMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A K336 Y350 F356 G357 E358 L359 A360 R367 A368 A369 Y405 K192 Y206 F212 G213 E214 L215 A216 R223 A224 A225 Y261
BS02 CMP A C212 K224 F232 G233 E234 L235 A236 R243 A244 A245 C68 K80 F88 G89 E90 L91 A92 R99 A100 A101
Gene Ontology
Molecular Function
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5j3u, PDBe:5j3u, PDBj:5j3u
PDBsum5j3u
PubMed
UniProtA0A0F7V8B2

[Back to BioLiP]