Structure of PDB 5j2r Chain A

Receptor sequence
>5j2rA (length=82) Species: 9606 (Homo sapiens) [Search protein sequence]
SPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRI
QDGEKKPIGWDTDISWLTGEELHVEVLENVPL
3D structure
PDB5j2r A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6FS A K154 Q165 R166 T167 V168 M187 R188 K4 Q15 R16 T17 V18 M37 R38
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:5j2r, PDBe:5j2r, PDBj:5j2r
PDBsum5j2r
PubMed27104980
UniProtP15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf (Gene Name=BRAF)

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