Structure of PDB 5izu Chain A

Receptor sequence
>5izuA (length=124) Species: 10090 (Mus musculus) [Search protein sequence]
RTKRLFRHYTVGSYDSLTSHSDYVIDDKVAILQKRDHEGFGFVLRGAKAE
TPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVG
HKQVVGLIRQGGNRLVMKVVSVTR
3D structure
PDB5izu A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function
ChainA
Resolution2.494 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G580 F581 F583 V584 L585 R586 G587 A588 K589 Y608 E610 H642 G39 F40 F42 V43 L44 R45 G46 A47 K48 Y67 E69 H101
BS02 peptide A T543 K544 R545 L546 F547 R548 H549 Y550 T551 T2 K3 R4 L5 F6 R7 H8 Y9 T10
External links
PDB RCSB:5izu, PDBe:5izu, PDBj:5izu
PDBsum5izu
PubMed27185935
UniProtQ4ACU6|SHAN3_MOUSE SH3 and multiple ankyrin repeat domains protein 3 (Gene Name=Shank3)

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