Structure of PDB 5iyy Chain A

Receptor sequence
>5iyyA (length=156) Species: 9606 (Homo sapiens) [Search protein sequence]
MFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDS
YREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWIT
IKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEV
YGCKIT
3D structure
PDB5iyy Architecture and hydration of the arginine-binding site of neuropilin-1.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R40 A Y297 W301 T316 D320 S346 T349 Y353 G414 I415 Y26 W30 T45 D49 S75 T78 Y82 G143 I144 PDBbind-CN: -logKd/Ki=4.77,Kd=17uM
External links
PDB RCSB:5iyy, PDBe:5iyy, PDBj:5iyy
PDBsum5iyy
PubMed29430837
UniProtO14786|NRP1_HUMAN Neuropilin-1 (Gene Name=NRP1)

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