Structure of PDB 5iwy Chain A

Receptor sequence
>5iwyA (length=158) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACL
GAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTII
AQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQ
ATVLIQKG
3D structure
PDB5iwy Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly among IspD/IspE/IspF enzymes in the MEP pathway.
ChainA
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.12: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D9 H11 H43 D9 H11 H43
BS02 C5P A A101 K105 M106 L107 A132 T133 T134 E136 A101 K105 M106 L107 A132 T133 T134 E136
BS03 C5P A D57 G59 D57 G59
Gene Ontology
Molecular Function
GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:5iwy, PDBe:5iwy, PDBj:5iwy
PDBsum5iwy
PubMed29335298
UniProtQ06756|ISPF_BACSU 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (Gene Name=ispF)

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