Structure of PDB 5itv Chain A

Receptor sequence
>5itvA (length=255) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
MIMNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRK
ENNDRLHFVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHE
MELSDWNKVLQVNLTGMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPD
IPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGIIDTPLNEKSFLENN
EGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTGSAITADG
GYTAQ
3D structure
PDB5itv Probing the influence of non-covalent contact networks identified by charge density analysis on the oxidoreductase BacC.
ChainA
Resolution2.26 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G18 S141 Y154 K158
Catalytic site (residue number reindexed from 1) G18 S141 Y154 K158
Enzyme Commision number 1.1.1.385: dihydroanticapsin 7-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAI A G14 S17 G18 I19 D38 I39 T61 I63 N89 G91 T139 S141 Y154 K158 P184 G185 I186 I187 G14 S17 G18 I19 D38 I39 T61 I63 N89 G91 T139 S141 Y154 K158 P184 G185 I186 I187
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5itv, PDBe:5itv, PDBj:5itv
PDBsum5itv
PubMed28158843
UniProtP39640|BACC_BACSU Dihydroanticapsin 7-dehydrogenase (Gene Name=bacC)

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