Structure of PDB 5itp Chain A

Receptor sequence
>5itpA (length=254) Species: 358 (Agrobacterium tumefaciens) [Search protein sequence]
YKSITIATEGSYAPYNFKDAGGKLIGFDIDLGNDLCKRMNIECKFVEQAW
DGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYLLTPMTFLTTADSPL
LKTQVAIENLPLDNITPEQKAELDKFTKIFEGVKFGVQAGTSHEAFMKQM
MPSVQISTYDTIDNVVMDLKAGRIDASLASVSFLKPLTDKPDNKDLKMFG
PRMTGGLFGKGVGVGIRKEDADLKALFDKAIDAAIADGTVQKLSQQWFGY
DASP
3D structure
PDB5itp Fitness costs restrict niche expansion by generalist niche-constructing pathogens.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6DB A E36 Y39 Y42 W77 A94 A95 G97 R102 M117 Q165 T168 H170 S207 E9 Y12 Y15 W50 A67 A68 G70 R75 M90 Q138 T141 H143 S180 MOAD: Kd=9.9uM
PDBbind-CN: -logKd/Ki=5.00,Kd=9.9uM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0071705 nitrogen compound transport
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Biological Process
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Cellular Component
External links
PDB RCSB:5itp, PDBe:5itp, PDBj:5itp
PDBsum5itp
PubMed27801902
UniProtP35120|NOCT_AGRFC Nopaline-binding periplasmic protein (Gene Name=nocT)

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