Structure of PDB 5ith Chain A

Receptor sequence
>5ithA (length=80) Species: 9606 (Homo sapiens) [Search protein sequence]
GNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFV
SFFNKWDAENAIQQMGGQWLGGRQIRTNWA
3D structure
PDB5ith TIA-1 RRM23 binding and recognition of target oligonucleotides.
ChainA
Resolution2.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A F98 D101 R125 K136 Y138 F140 R167 N169 A171 F7 D10 R34 K45 Y47 F49 R76 N78 A80 PDBbind-CN: Kd=0.03uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5ith, PDBe:5ith, PDBj:5ith
PDBsum5ith
PubMed28184449
UniProtP31483|TIA1_HUMAN Cytotoxic granule associated RNA binding protein TIA1 (Gene Name=TIA1)

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