Structure of PDB 5isx Chain A

Receptor sequence
>5isxA (length=529) Species: 1393 (Brevibacillus brevis) [Search protein sequence]
IEETLVTIWQDVLGIEKIGIKDNFYALGGDSIKAIQVAARLHSYQLKLET
KDLLKYPTIDQLVHYIKDSKRRSEQGIVEGEIGLTPIQHWFFEQQFTNMH
HWNQSYMLYRPNGFDKEILLRVFNKIVEHHDALRMIYKHHNGKIVQINRG
LEGTLFDFYTFDLTANDNEQQVICEESARLQNSINLEVGPLVKIALFHTQ
NGDHLFMAIHHLVVDGISWRILFEDLATAYEQAMHQQTIALPEKTDSFKD
WSIELEKYANSELFLEEAEYWHHLNYYTDNVQIKKDYVTMNNKQKNIRYV
GMELTIEETEKLLKNVNKAYRTEINDILLTALGFALKEWADIDKIVINLE
GHGREEILEQMNIARTVGWFTSQYPVVLDMQKSDDLSYQIKLMKENLRRI
PNKGIGYEIFKYLTTEYLRPVLPFTLKPEINFNYLGQFDTDVKTELFTRS
PYSMGNSLGPDGKNNLGPEGESYFVLNINGFIEEGKLHITFSYNEQQYKE
DTIQQLSRSYKQHLLAIIEHCVQKEDTEL
3D structure
PDB5isx Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases.
ChainA
Resolution2.335 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 5.1.1.11: phenylalanine racemase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PNS A S573 I574 H753 N867 G893 H894 T913 K945 Y976 L977 S31 I32 H211 N325 G351 H352 T371 K403 Y434 L435
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:5isx, PDBe:5isx, PDBj:5isx
PDBsum5isx
PubMed27294598
UniProtP0C062|GRSA_BREBE Gramicidin S synthase 1 (Gene Name=grsA)

[Back to BioLiP]