Structure of PDB 5ijl Chain A

Receptor sequence
>5ijlA (length=943) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence]
PKEMEEYFEMLQREIDKAYEIAKKARAQGKDPSLDVEIPQATDMAGRVES
LVGPPGVAKRIRELVKEYGKEIAALKIVDEIIEGKFGDLGSREKYAEQAV
RTALAILTEGIVSAPIEGIANVKIKRNTWADNSEYLALYYAGPIRSSGGT
AQALSVLVGDYVRRKLGLDRFKPSEKHIERMVEEVDLYHRAVTRLQYHPS
PEEVRLAMRNIPIEITGEATDDVEVSHRDVPGVETNQLRGGAILVLAEGV
LQKAKKLVKYIDKMGIEGWEWLKEFVEAKEKGVDMGFYYSLYQKFKEEPL
FSDPSKPGGFRLRYGRSWGINPATMILVGAVVTPVTTIEGPIVKLKDGSV
LRVDDYNLALKVREDVEEILYLGDAVIAFGDQTLLPANYCEEWWILEFVK
ALKEIYEVHLEPFTENEEESIEEASDYLEIDPEFLKEMLRDPLRVKPPVE
LAIHFSEVLGIPLHPYYTLYWNSVEPKDVEKLWRLLKNYAEIEWSNFRGI
KFAKKIVISQEKLGDSKRTLELLGLPHTVRDGNVIVDYPWAAALLTPLGN
LNWEFMAKPLYATIDIINENNEIKLRDRGISWIGKPPVQVLFPIGLAGGS
SRDIKKAAEEGKVAEVEIAFFKCPKCGHVGPEHLCPNCGTRKELLWVCPR
CNAEYPESQAEGYNYTCPKCNVKLRPYAKRKIRPSELLNRAMENVKVYGV
DKLKGVMGMTSGWKMPEPLEKGLLRAKNDVYVFKDGTIRFDATDAPITHF
RPREIGVSVEKLRELGYTHDFEGKPLVSEDQIVELKPQDIILSKEAGRYL
LKVAKFVDDLLEKFYGLPRFYNAEKMEDLIGHLVIGLAPHTSAGIVGRII
GFVDALVGYAHPYFHAAKRRNCDGDEDAVMLLLDALLNFSRYYLPEKRGG
KMDAPLVITTRLDPRYYPLEFYEATYELKSPKELVGVIERVED
3D structure
PDB5ijl Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography.
ChainA
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.1: exodeoxyribonuclease I.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C706 C709 C718 C623 C626 C635
BS02 ZN A C731 C734 C750 C753 C648 C651 C667 C670
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:5ijl, PDBe:5ijl, PDBj:5ijl
PDBsum5ijl
PubMed27548043
UniProtQ9V2F4|DP2L_PYRAB DNA polymerase II large subunit (Gene Name=polC)

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