Structure of PDB 5ii1 Chain A

Receptor sequence
>5ii1A (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
SKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIK
KPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV
LHKVLLETRRDL
3D structure
PDB5ii1 Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
ChainA
Resolution2.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6BL A I683 F684 L687 Y696 M704 A735 I745 I32 F33 L36 Y45 M53 A84 I94 PDBbind-CN: -logKd/Ki=5.48,Kd=3.3uM
Gene Ontology
Biological Process
GO:0006338 chromatin remodeling
Cellular Component
GO:0016586 RSC-type complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5ii1, PDBe:5ii1, PDBj:5ii1
PDBsum5ii1
PubMed27617704
UniProtQ86U86|PB1_HUMAN Protein polybromo-1 (Gene Name=PBRM1)

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