Structure of PDB 5ihr Chain A

Receptor sequence
>5ihrA (length=968) Species: 425011 (Aspergillus niger CBS 513.88) [Search protein sequence]
LLQKYVTWDDKSLFINGERIMIFSGEFHPFRLPVKELQLDIFQKVKALGF
NCVSFYVDWALVEGKPGEYRADGIFDLEPFFDAASEAGIYLLARPGPYIN
AESSGGGFPGWLQRVNGTLRSSDKAYLDATDNYVSHVAATIAKYQITNGG
PIILYQPENEYTSGCCGVEFPDPVYMQYVEDQARNAGVVIPLINNDASAS
GNNAPGTGKGAVDIYGHDSYPLGFDCANPTVWPSGDLPTNFRTLHLEQSP
TTPYAIVQFQGGSYDPWGGPGFAACSELLNNEFERVFYKNDFSFQIAIMN
LYMIFGGTNWGNLGYPNGYTSYDYGSAVTESRNITREKYSELKLLGNFAK
VSPGYLTASPGNLTTSGYADTTDLTVTPLLGNSTGSFFVVRHSDYSSEES
TSYKLRLPTSAGSVTIPQLGGTLTLNGRDSKIHVTDYNVSGTNIIYSTAE
VFTWKKFADGKVLVLYGGAGEHHELAISTKSNVTVIEGSESGISSKQTSS
SVVVGWDVSTTRRIIQVGDLKILLLDRNSAYNYWVPQLATDGTSPGFSTP
EKVASSIIVKAGYLVRTAYLKGSGLYLTADFNATTSVEVIGVPSTAKNLF
INGDKTSHTVDKNGIWSATVDYNAPDISLPSLKDLDWKYVDTLPEIQSSY
DDSLWPAADLKQTKNTLRSLTTPTSLYSSDYGFHTGYLLYRGHFTATGNE
STFAIDTQGGSAFGSSVWLNGTYLGSWTGLYANSDYNATYNLPQLQAGKT
YVITVVIDNMGLEENWTVGEDLMKTPRGILNFLLAGRPSSAISWKLTGNL
GGEDYEDKVRGPLNEGGLYAERQGFHQPEPPSQNWKSSSPLEGLSEAGIG
FYSASFDLDLPKGWDVPLFLNIGNSTTPSPYRVQVYVNGYQYAKYISNIG
PQTSFPVPEGILNYRGTNWLAVTLWALDSAGGKLESLELSYTTPVLTALG
EVESVDQPKYKKRKGAYH
3D structure
PDB5ihr Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.23: beta-galactosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A N911 E978 S980 N871 E938 S940
BS02 MAN A E377 N568 E337 N528
BS03 MAN A E322 R325 E282 R285
BS04 MAN A W307 G308 Y771 W267 G268 Y731
BS05 MAN A Y771 A772 Y731 A732
BS06 GAL A N140 A141 E142 E200 Q298 Y342 Y364 N100 A101 E102 E160 Q258 Y302 Y324
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5ihr, PDBe:5ihr, PDBj:5ihr
PDBsum5ihr
PubMed28391618
UniProtA2QAN3|BGALA_ASPNC Beta-galactosidase A (Gene Name=lacA)

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