Structure of PDB 5ign Chain A

Receptor sequence
>5ignA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SKERLLALKRSMS
3D structure
PDB5ign Crystal structure of BRD9 bromodomain in complex with LP99 chemical probe
ChainA
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6B2 A H42 G43 F44 F45 P48 T50 I53 N100 Y106 H21 G22 F23 F24 P27 T29 I32 N79 Y85 BindingDB: Kd=99nM,IC50=6200nM
External links
PDB RCSB:5ign, PDBe:5ign, PDBj:5ign
PDBsum5ign
PubMed
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

[Back to BioLiP]