Structure of PDB 5ib4 Chain A

Receptor sequence
>5ib4A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB5ib4 Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 H9 T24 E45 R62 E63 Q65 I66 C67 T73 E76 D77 Y84 Y99 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171 Y7 H9 T24 E45 R62 E63 Q65 I66 C67 T73 E76 D77 Y84 Y99 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171
External links
PDB RCSB:5ib4, PDBe:5ib4, PDBj:5ib4
PDBsum5ib4
PubMed31296658
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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