Structure of PDB 5i7y Chain A

Receptor sequence
>5i7yA (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
S
3D structure
PDB5i7y Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.
ChainA
Resolution1.4514 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 69G A F44 F45 V49 I53 N100 Y106 F23 F24 V28 I32 N79 Y85 MOAD: Kd=52nM
PDBbind-CN: -logKd/Ki=7.28,Kd=52nM
External links
PDB RCSB:5i7y, PDBe:5i7y, PDBj:5i7y
PDBsum5i7y
PubMed27219867
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

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