Structure of PDB 5i70 Chain A

Receptor sequence
>5i70A (length=315) Species: 57266 (Plasmodium falciparum 7G8) [Search protein sequence]
SIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCST
KHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIE
VTDADDLEPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALF
TFYLPVHDHVGYLTIGGIESDFYEGPLTYEKLNHDLYWQIDLDIHFGKYV
MQKANAVVDSGTSTITAPTSFLNKFFVIKVPFYVTTCDNDDLPTLEFHSR
NNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDDNTFILGDPFMRKYFTV
FDYEKESVGFAVAKN
3D structure
PDB5i70 Crystal Structure of plasmepsin IV
ChainA
Resolution3.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D34 S37 N39 W41 Y77 D214 T217
Catalytic site (residue number reindexed from 1) D30 S33 N35 W37 Y73 D209 T212
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D34 G36 S76 Y77 G78 S79 I123 Y192 D214 G216 T217 S218 I294 D30 G32 S72 Y73 G74 S75 I119 Y187 D209 G211 T212 S213 I282
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5i70, PDBe:5i70, PDBj:5i70
PDBsum5i70
PubMed
UniProtW7FF86

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