Structure of PDB 5i49 Chain A

Receptor sequence
>5i49A (length=471) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
VRLYSCDACPHAVFTTHAALLAHAEEHHADLLPDHARLRRIAQKLNPVWN
RALNARRNTITSWGKKIFHVAAQRDAGESKMQEAHRARAQLECVVRRWHD
KARVFIFGSSVAMGVWDGTADIDFAVVDVDAMERGSWPPLEKNAVRSITE
LLRRVGFSFVNLEPISHARVPIIKHHASSPDVVARSIRFILNGPATREDR
LLLEGSVRDAVGPTGVQQVWWNRTSDMMSATLESTTAAVRAAMCSPALAS
ASLRTKVQPAHDECRPELYNIDFDLSFRAFGIRNSTLLRKYLLSHPCARP
GAIVLKDWSKTSGVNNSVNGYFTSYAINIMWIYYLVQKGYVPYVDPLEIP
ESLVNYTDFDPRYTPMIDPEITNTEREELYKAAGDMLVGFFYFYSFEFDW
GHNVISLNRPGITTKRMLGWHVEDVHPTRYELCIEDPYEENLNLGRHIGV
TKSLRVRTELYRGLLSLLKEG
3D structure
PDB5i49 RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C195 C198 H212 H217 C6 C9 H23 H28
BS02 2KH A F479 G480 N483 S484 K505 K509 S523 Y524 F280 G281 N284 S285 K306 K310 S324 Y325
External links
PDB RCSB:5i49, PDBe:5i49, PDBj:5i49
PDBsum5i49
PubMed27744351
UniProtQ8WQX5|TUT1_TRYBB Terminal uridylyltransferase 1 (Gene Name=KRET1)

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