Structure of PDB 5i40 Chain A

Receptor sequence
>5i40A (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SK
3D structure
PDB5i40 Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.
ChainA
Resolution1.0402 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 67N A F44 F45 V49 I53 N100 Y106 F23 F24 V28 I32 N79 Y85 MOAD: ic50=13.7uM
PDBbind-CN: -logKd/Ki=4.86,IC50=13.7uM
BindingDB: IC50=13700nM
External links
PDB RCSB:5i40, PDBe:5i40, PDBj:5i40
PDBsum5i40
PubMed27219867
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

[Back to BioLiP]