Structure of PDB 5i23 Chain A

Receptor sequence
>5i23A (length=779) Species: 498211 (Cellvibrio japonicus Ueda107) [Search protein sequence]
AVFYKEHKLRNDGLVITTNQGNIRLQFKSEAAIEVLYRADSKQLPSFALA
QPESAIKAQLTETENHLQFSGGTLTARIQKRPFAISYYRDSELLLAEESG
FQKINFRFYLSPGEKILGGGQRILGMDRRGQRFPLYNRAHYGYSDHSGQM
YFGLPAIMSSKQYILVFDNSASGAMDIGKTESDILQLEAKSGRSAYILVA
GNSYPSLIENFTQVTGRQPLPPRWALGSFASRFGYRSEAETRATVQKYKT
EDFPLDTIVLDLYWFGKDIKGHMGNLDWDKENFPTPLDMMADFKQQGVKT
VLITEPFVLTSSKRWDDAVKAKALAKDPQGQPKAFELYFGNGGIIDVFSK
EGSRWFSSIYKDLSKQGVAGWWGDLGEPEMHPEDTQHAIGDADTVHNAYG
HRWAEMLYQQQLDQFPELRPFIMMRAGFVGSQRYGMIPWTGDVSRTWGGL
ASQVELALQMSLLGFGYIHSDLGGFADGETLDKEMYIRWLQYGVFQPVYR
PHGQDHIPSEPVFQDEETKAILRPLVKLRYRMLPYIYTAAYQNTLTGMPL
MRPLFFSDEKNPALIDNKTSYFWGDSLLVTPITQAGVESVSIPAPKGVWF
DFWKDTRYQTDGAPLTLPTDLHTIPVLVKAGAFMPYVPAVSTTEDYRSDS
LEIHYYADASVPLAQGEIFEDDGKDPNSIKRNQFDLLTLQATHTDNQLHF
QLARTGKGYRGMPERRATTLVIHNASDQYQHLDINGKTIAIAQADCASTP
ALACYDQERRQLQLVFTWGREALNLRLHK
3D structure
PDB5i23 Detection of Active Mammalian GH31 alpha-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.161: oligosaccharide 4-alpha-D-glucosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 66V A F271 D299 Y376 W410 D412 R463 W477 D480 F513 H540 F233 D261 Y338 W372 D374 R425 W439 D442 F475 H502 PDBbind-CN: -logKd/Ki=7.29,IC50=51.7nM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016757 glycosyltransferase activity
GO:0030246 carbohydrate binding
GO:0033825 oligosaccharide 4-alpha-D-glucosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5i23, PDBe:5i23, PDBj:5i23
PDBsum5i23
PubMed27280170
UniProtB3PEE6|OL4AG_CELJU Oligosaccharide 4-alpha-D-glucosyltransferase (Gene Name=agd31B)

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