Structure of PDB 5i04 Chain A

Receptor sequence
>5i04A (length=668) Species: 9606,83333 [Search protein sequence]
GTKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFP
QVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVR
YNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALM
FNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDL
IKNKHMNADTDYSIAEHAFNHGETAMTINGPWAWSNIDTSAVNYGVTVLP
TFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKP
LGAVALKSYEEELVKDPRVAATMENAQKGEIMPNIPQMSAFWYAVRTAVI
NAASGRQTVDAALAAAQTNAAAETVHCDLQPVGPERGEVTYTTSQVSKGC
VAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQPREVLLVLSVNSSVFL
HLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPIT
SAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGC
HLEGVAGHKEAHILRVLPAGPRTVTVKVELSCAPGDLDAVLILQGPPYVS
WLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASI
VASFVELPLASIVSLHAS
3D structure
PDB5i04 Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
ChainA
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A D69 K70 E166 Y210 F211 D16 K17 E113 Y157 F158
BS02 GLC A W117 D120 R121 E208 P209 Y210 W395 W64 D67 R68 E155 P156 Y157 W342
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5i04, PDBe:5i04, PDBj:5i04
PDBsum5i04
PubMed28564608
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
P17813

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