Structure of PDB 5hyj Chain A

Receptor sequence
>5hyjA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB5hyj A "hotspot" for autoimmune T cells in type 1 diabetes.
ChainA
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 M45 Y59 E63 K66 H70 T73 D77 Y84 R97 Y99 H114 T143 K146 W147 L156 Y159 W167 Y171 Y7 M45 Y59 E63 K66 H70 T73 D77 Y84 R97 Y99 H114 T143 K146 W147 L156 Y159 W167 Y171
External links
PDB RCSB:5hyj, PDBe:5hyj, PDBj:5hyj
PDBsum5hyj
PubMed27183386
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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