Structure of PDB 5hva Chain A

Receptor sequence
>5hvaA (length=140) Species: 1299 (Deinococcus radiodurans) [Search protein sequence]
PCPPTNAERLHEFHRAIGAATPERPTPPPPELLRLRQTLLDEESAEVRAE
IDHLLARQAAGEALSAGDLAPLAHELADLLYVTYGALDQLGIDADAVFAE
VHRANLSKASGPRRADGKQLKPEGWRPADVRGVIERLQHA
3D structure
PDB5hva Deinococcus radiodurans DR2231 is a two-metal-ion mechanism hydrolase with exclusive activity on dUTP.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A E47 E50 E79 D82 E43 E46 E75 D78
BS02 DUP A N109 K112 K122 Q123 N105 K108 K118 Q119 PDBbind-CN: -logKd/Ki=7.07,Kd=0.086uM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:5hva, PDBe:5hva, PDBj:5hva
PDBsum5hva
PubMed27739259
UniProtQ9RS96

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