Structure of PDB 5hv4 Chain A

Receptor sequence
>5hv4A (length=193) Species: 1392 (Bacillus anthracis) [Search protein sequence]
TNNNQIEQTIFDHKGNVIKTEDREIQIISKFEEPLIVVLGNVLSDEECDE
LIELSKSKLAAFLDDNELTAKIEKRISSIMNVPASHGEGLHILNYEVDQQ
YKAHYDYFAEHSRSAANNRISTLVMYLNDVEEGGETFFPKLNLSVHPRKG
MAVYFEYFYQDQSLNELTLHGGAPVTKGEKWIATQWVRRGTYK
3D structure
PDB5hv4 Structural analysis of cofactor binding for a prolyl 4-hydroxylase from the pathogenic bacterium Bacillus anthracis.
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CD A H127 D129 H193 H104 D106 H170
BS02 CD A D17 N104 D12 N81
BS03 AKG A T159 G195 K203 I205 T207 T136 G172 K180 I182 T184 MOAD: Kd=1.1uM
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0004656 procollagen-proline 4-dioxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0031418 L-ascorbic acid binding
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0008150 biological_process
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline

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Molecular Function
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Biological Process
External links
PDB RCSB:5hv4, PDBe:5hv4, PDBj:5hv4
PDBsum5hv4
PubMed27139630
UniProtA0A4Y1WAP5

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