Structure of PDB 5hv0 Chain A

Receptor sequence
>5hv0A (length=206) Species: 1392 (Bacillus anthracis) [Search protein sequence]
NQIKEQTIFDHKGNVIKTEDREIQIISKFEEPLIVVLGNVLSDEECDELI
ELSKSKLARSKVGSSNDIRTSSGAFLDDNELTAKIEKRISSIMNVPASHG
EGLHILNYEVDQQYKAHYDYFAEHSRSAANNRISTLVMYLNDVEEGGETF
FPKLNLSVHPRKGMAVYFEYFYQDQSLNELTLHGGAPVTKGEKWIATQWV
RRGTYK
3D structure
PDB5hv0 Structural analysis of cofactor binding for a prolyl 4-hydroxylase from the pathogenic bacterium Bacillus anthracis.
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CD A H127 D129 H193 H117 D119 H183
BS02 CD A E119 G201 E109 G191
BS03 AKG A Y118 H127 T159 H193 K203 I205 T207 W209 Y108 H117 T149 H183 K193 I195 T197 W199 MOAD: Kd=1.1uM
PDBbind-CN: -logKd/Ki=5.96,Kd=1.1uM
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0004656 procollagen-proline 4-dioxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0031418 L-ascorbic acid binding
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0008150 biological_process
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5hv0, PDBe:5hv0, PDBj:5hv0
PDBsum5hv0
PubMed27139630
UniProtA0A4Y1WAP5

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