Structure of PDB 5hsw Chain A

Receptor sequence
>5hswA (length=428) Species: 435895 (Human herpesvirus 8 type M) [Search protein sequence]
TPADLFSEDAVLASLSFSKFLKHAKVRDWCAQAKIQPSMPALRMAYNYFL
FSKVGEFIGSEDVCNFFVDRVFGGVRLLDVASVYAACSQMNAHQRHHICC
LVERATSSQSLNPVWDALRDGIISSSKFHWAVKQQNKIFSPPLAFGLRCE
EVVKTLLATLLHPDETNCLDYGFMQSPQNGIFGVSLDFAANVKTDTGRLQ
FDPNCKVYSIKCRFKYTFAKMECDPIYAAYQRLYEAPGKLALKDFFYSIS
KPAVEYVGLGKLPSESDYLVAYDQEWEACLHNLIRECILHNSTTESDVYV
LTDPQDTRGQISIKARFKANLFVNVRHSYFYQVLLQSSIVEEYIGSPKYY
IATGFFRKRGYQDPVNCTIGGDALDPHVEIPTLLIVTPVYFPRGAKHRLL
HQAANFWSRSAKDTFPYIKWDFSYLSAN
3D structure
PDB5hsw KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A F179 K246 C247 R248 F249 Y373 F145 K211 C212 R213 F214 Y329 PDBbind-CN: Kd=48.9uM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:5hsw, PDBe:5hsw, PDBj:5hsw
PDBsum5hsw
PubMed28132029
UniProtP88925

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