Structure of PDB 5hrx Chain A

Receptor sequence
>5hrxA (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
YMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKP
MDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLH
KVLLETRRDL
3D structure
PDB5hrx Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
ChainA
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 64F A I683 F684 L687 Y696 M704 A735 I30 F31 L34 Y43 M51 A82 PDBbind-CN: -logKd/Ki=5.29,Kd=5.1uM
Gene Ontology
Biological Process
GO:0006338 chromatin remodeling
Cellular Component
GO:0016586 RSC-type complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5hrx, PDBe:5hrx, PDBj:5hrx
PDBsum5hrx
PubMed27617704
UniProtQ86U86|PB1_HUMAN Protein polybromo-1 (Gene Name=PBRM1)

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