Structure of PDB 5hrr Chain A

Receptor sequence
>5hrrA (length=140) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTIHTDNGSNFTSNSVKAACWWAGIKQEGVVESMNKELKKIIGQV
RDQAEHLKTAVQMAVFIHNKKRKGYSAGERIVDIIATDIQ
3D structure
PDB5hrr Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
ChainA
Resolution1.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 65P A A169 E170 H171 T174 M178 A104 E105 H106 T109 M113
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:5hrr, PDBe:5hrr, PDBj:5hrr
PDBsum5hrr
PubMed27935939
UniProtP04585|POL_HV1H2 Gag-Pol polyprotein (Gene Name=gag-pol)

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