Structure of PDB 5hrf Chain A

Receptor sequence
>5hrfA (length=178) Species: 10497 (African swine fever virus) [Search protein sequence]
SGGGMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKM
LNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKT
YQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQ
TLVPLKITTEKELIKELGFTYRIPKKRL
3D structure
PDB5hrf The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
ChainA
Resolution2.25 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A V80 C81 G82 R84 K85 I124 R127 K131 K136 L137 N138 Y140 V84 C85 G86 R88 K89 I128 R131 K135 K140 L141 N142 Y144
BS02 MN A D49 D51 D53 D55
BS03 DGT A G38 S39 R42 N48 D49 D51 H115 F116 T117 V120 R127 G42 S43 R46 N52 D53 D55 H119 F120 T121 V124 R131
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0044423 virion component

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5hrf, PDBe:5hrf, PDBj:5hrf
PDBsum5hrf
PubMed
UniProtP42494|DPOLX_ASFB7 Repair DNA polymerase X (Gene Name=Ba71V-97)

[Back to BioLiP]