Structure of PDB 5hp0 Chain A

Receptor sequence
>5hp0A (length=122) Species: 9606,10090 [Search protein sequence]
SPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKT
NGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQGSGSGSQA
MDDLMLSPDDIEQWFTEDPGPD
3D structure
PDB5hp0 Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H1782 C1786 C1791 C1796 H19 C23 C28 C33
BS02 ZN A H1805 C1809 C1817 H42 C46 C54
BS03 ZN A H1830 C1834 C1839 C1844 H67 C71 C76 C81
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5hp0, PDBe:5hp0, PDBj:5hp0
PDBsum5hp0
PubMed26976603
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53);
P45481|CBP_MOUSE Histone lysine acetyltransferase CREBBP (Gene Name=Crebbp)

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