Structure of PDB 5hou Chain A

Receptor sequence
>5houA (length=171) Species: 9606,10090 [Search protein sequence]
GSHMEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSP
DDIEQWFTEDPGPDGSCFNGTATGPTADPEKRKLIQQQLVLLLHAHKCQR
REQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHW
KNCTRHDCPVCLPLKNASDKR
3D structure
PDB5hou Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H3362 C3366 C3379 H94 C98 C111
BS02 ZN A H3393 C3397 C3403 C3408 H125 C129 C135 C140
BS03 ZN A H3417 C3421 C3426 H149 C153 C158
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5hou, PDBe:5hou, PDBj:5hou
PDBsum5hou
PubMed26976603
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53);
P45481|CBP_MOUSE Histone lysine acetyltransferase CREBBP (Gene Name=Crebbp)

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