Structure of PDB 5ho4 Chain A

Receptor sequence
>5ho4A (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
REKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGF
GFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKL
FVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD
PVDKIVLQKYHTINGHNAEVRKALSRQEM
3D structure
PDB5ho4 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Q19 K22 F24 G26 G27 D49 V51 M53 R62 G63 F64 F66 E92 A96 V97 R99 Q5 K8 F10 G12 G13 D35 V37 M39 R48 G49 F50 F52 E78 A82 V83 R85 PDBbind-CN: Kd=114.7nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5ho4, PDBe:5ho4, PDBj:5ho4
PDBsum5ho4
PubMed29379020
UniProtP22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (Gene Name=HNRNPA2B1)

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