Structure of PDB 5hmp Chain A

Receptor sequence
>5hmpA (length=697) Species: 9606 (Homo sapiens) [Search protein sequence]
ELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNP
LPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILV
AMNPYKQLPIYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQS
IIVSGESGAGKTVSARYAMRYFATVSKSAHVEDKVLASNPITEAVGNAKT
TRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVFQSENERNYHI
FYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKT
FTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFC
ELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHL
FDFIVERINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKL
QQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKMGILELLDE
ECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSNTSFVIQHFADKVEYKC
EGFLEKNRDTVYDMLVEILRASKFHLCANFFQENRTTVGSKFRSSLYLLM
ETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSY
PSRWTYIEFYSRKKEVCKVVLHRDSNQYQFGKTKIFFRAGQVAYLEK
3D structure
PDB5hmp The myosin X motor is optimized for movement on actin bundles.
ChainA
Resolution2.397 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S163 G164 T168 N212 S215 S216 G438 E440
Catalytic site (residue number reindexed from 1) S157 G158 T162 N203 S206 S207 G429 E431
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T168 S216 T162 S207
BS02 ADP A N109 P110 K112 G164 G166 K167 T168 V169 N212 N103 P104 K106 G158 G160 K161 T162 V163 N203
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5hmp, PDBe:5hmp, PDBj:5hmp
PDBsum5hmp
PubMed27580874
UniProtQ9NQX4|MYO5C_HUMAN Unconventional myosin-Vc (Gene Name=MYO5C)

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