Structure of PDB 5hle Chain A

Receptor sequence
>5hleA (length=303) Species: 7227,10116 [Search protein sequence]
NTVMDLRGNIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIQGKPYVFD
RVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKL
HDPQLMGIIPRIAHDIFDHIYSMDENLEFAIKVSYFEIYLDKIRDLLDVS
KTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKSNRHVAEHSSRS
HSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVKNINKSLSALGNVISA
LAEGTTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLM
FAA
3D structure
PDB5hle Backwards motion in kinesin-14 requires neck-mimic to control a neck-helix swing.
ChainA
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R32 P33 S104 S105 G106 K107 T108 H109 R17 P18 S89 S90 G91 K92 T93 H94
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5hle, PDBe:5hle, PDBj:5hle
PDBsum5hle
PubMed
UniProtP20480|NCD_DROME Protein claret segregational (Gene Name=ncd);
P56536|KIF5C_RAT Kinesin heavy chain isoform 5C (Gene Name=Kif5c)

[Back to BioLiP]