Structure of PDB 5hkp Chain A

Receptor sequence
>5hkpA (length=313) Species: 10090 (Mus musculus) [Search protein sequence]
VLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAG
YNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV
NAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTP
ELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHC
AVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLH
KHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAA
QMGNEAVQQILSE
3D structure
PDB5hkp Crystal structure of a tankyrase 1-telomere repeat factor 1 complex.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R361 S363 L368 G371 Y372 L396 N401 Y405 H407 D425 W427 F429 E434 R440 R40 S42 L47 G50 Y51 L75 N80 Y84 H86 D104 W106 F108 E113 R119
External links
PDB RCSB:5hkp, PDBe:5hkp, PDBj:5hkp
PDBsum5hkp
PubMed27050267
UniProtQ6PFX9|TNKS1_MOUSE Poly [ADP-ribose] polymerase tankyrase-1 (Gene Name=Tnks)

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