Structure of PDB 5hio Chain A

Receptor sequence
>5hioA (length=301) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
HMLRLSAPGQLDDDLCLLGDVQVPVFLLRLGEASWALVEGGISRDAELVW
ADLCRWVADPSQVHYWLITHKHYDHCGLLPYLCPRLPNVQVLASERTCQA
WKSESAVRVVERLNRQLLRAEQRLPEACAWDALPVRAVADGEWLELGPRH
RLQVIEAHGHSDDHVVFYDVRRRRLFCGDALGEFDEAEGVWRPLVFDDME
AYLESLERLQRLPTLLQLIPGHGGLLRGRLAADGAESAYTECLRLCRRLL
WRQSMGESLDELSEELHRAWGGQSVDFLPGELHLGSMRRMLEILSRQALP
L
3D structure
PDB5hio Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.2.32: 2-aminobenzoylacetyl-CoA thioesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H69 H71 H74 H159 D178 H70 H72 H75 H160 D179
BS02 FE A D73 H74 D178 H221 D74 H75 D179 H222
BS03 61M A H71 D73 H74 H159 D178 E182 L193 F195 H221 L277 H282 H72 D74 H75 H160 D179 E183 L194 F196 H222 L278 H283
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0044550 secondary metabolite biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5hio, PDBe:5hio, PDBj:5hio
PDBsum5hio
PubMed27082157
UniProtP20581|PQSE_PSEAE 2-aminobenzoylacetyl-CoA thioesterase (Gene Name=pqsE)

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