Structure of PDB 5hhp Chain A

Receptor sequence

>5hhpA (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPLTLRW

3D structure

PDB

5hhp Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.

Chain

Resolution

1.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y7 E63 R65 K66 V67 H70 T73 D77 L81 Y99 H114 Y116 T143 K146 W147 V152 L156 Y159 W167 Y171	Y7 E63 R65 K66 V67 H70 T73 D77 L81 Y99 H114 Y116 T143 K146 W147 V152 L156 Y159 W167 Y171

External links

PDB	RCSB:5hhp, PDBe:5hhp, PDBj:5hhp
PDBsum	5hhp
PubMed	27036003
UniProt	P04439\|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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