Structure of PDB 5hfk Chain A

Receptor sequence
>5hfkA (length=207) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MIDLYFAPTPNGHKITLFLEEAGLDYRLIKVDLGKGGQFRPEFLLISPNN
KIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQW
LFWQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLEN
SPWLGGENYSIADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATG
QALLKAQ
3D structure
PDB5hfk Structure and function of YghU, a nu-class glutathione transferase related to YfcG from Escherichia coli.
ChainA
Resolution1.551 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T9
Catalytic site (residue number reindexed from 1) T9
Enzyme Commision number 1.11.1.-
1.8.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A T9 N11 G109 P110 W169 T9 N11 G109 P110 W169
BS02 GSH A T9 N11 Q38 K51 I52 E71 S72 T9 N11 Q38 K51 I52 E71 S72
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0015036 disulfide oxidoreductase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006979 response to oxidative stress
GO:0098869 cellular oxidant detoxification

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Molecular Function
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Biological Process
External links
PDB RCSB:5hfk, PDBe:5hfk, PDBj:5hfk
PDBsum5hfk
PubMed
UniProtP77526|YFCG_ECOLI Disulfide-bond oxidoreductase YfcG (Gene Name=yfcG)

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