Structure of PDB 5hca Chain A

Receptor sequence
>5hcaA (length=266) Species: 294381 (Entamoeba histolytica HM-1:IMSS) [Search protein sequence]
SAKVYFHETFENRDKWIDSTSSGKALGPFKIVSGKWYGDANNKGLQTSED
NKFYIAAAKLDEEFSNKDKNLIVQYNLKFEQGIDCGGGYIKLLPKKSIES
EEKFTPESEYNIMFGPDVCGGSKRTHVIMNYKGKNNLIRKEIKCESDDIS
HLYTLIIRPNNTYVVKIDGVEKQEGKFDEDWDMLAPKEIDDGSGIANPDY
VYDPELYKYDSFAYIGIDVWQVKAGTIYDDILITDDIEEAEKEAKVILER
NAAEKKMRDEIKEAEN
3D structure
PDB5hca Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A T21 N54 K55 D323 T9 N42 K43 D229
BS02 BGC A K103 Y122 M125 K91 Y110 M113
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
Cellular Component
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5hca, PDBe:5hca, PDBj:5hca
PDBsum5hca
PubMed27840680
UniProtP83003|CALR_ENTH1 Calreticulin (Gene Name=CRT)

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