Structure of PDB 5h9r Chain A

Receptor sequence
>5h9rA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB5h9r Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TGZ A R144 I145 A146 H158 N160 R162 W181 E184 S237 R32 I33 A34 H46 N48 R50 W69 E72 S125 MOAD: Kd=0.84uM
PDBbind-CN: -logKd/Ki=6.08,Kd=0.84uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:5h9r, PDBe:5h9r, PDBj:5h9r
PDBsum5h9r
PubMed27416897
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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