Structure of PDB 5h5f Chain A

Receptor sequence
>5h5fA (length=224) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SHHHHHHLEVLFQGPHMASKYIIEHMEEGFSEWVILEYSQILREVGAENL
ILSSLPESTTEKDIPQRLLKLGLRWTTKDLKGINEDFKDLELLKDGRVCL
LDPRATIDLQPEDATKFDYFVFGGILGDHPPRDRTKELKTAYPNLLISRR
LGDKQMTTDTAIRTTQLIIKDRIAFEDIKFIDYPEFRFNKNEATEMPFRY
VLDKEGKPILPEGMLDLIKKDSAQ
3D structure
PDB5h5f A flexible cofactor-binding loop in the novel arginine methyltransferase Sfm1.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A L83 D84 P85 G105 D115 R116 T117 L133 Q137 M138 A143 L101 D102 P103 G123 D133 R134 T135 L151 Q155 M156 A161 MOAD: Kd=37.2uM
PDBbind-CN: -logKd/Ki=4.43,Kd=37.2uM
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0035241 protein-arginine omega-N monomethyltransferase activity
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5h5f, PDBe:5h5f, PDBj:5h5f
PDBsum5h5f
PubMed27990635
UniProtQ12314|SFM1_YEAST Protein arginine N-methyltransferase SFM1 (Gene Name=SFM1)

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