Structure of PDB 5h3u Chain A

Receptor sequence
>5h3uA (length=670) Species: 9606 (Homo sapiens) [Search protein sequence]
QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTP
PFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVV
TEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPR
TIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIA
WCPLPGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRVKERLWLTLHW
PSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASGQNHSRIVFNLCPL
QTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIG
SLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLA
FGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLALYSCG
GEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMA
LGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMAS
GSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHD
GRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGA
DDFCVHKWLTSMQDHSRPPQ
3D structure
PDB5h3u Structural basis for specific recognition of pre-snRNA by Gemin5
ChainA
Resolution2.499 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A N13 W14 Y15 R33 R66 R284 R335 R359 G380 F381 Y383 G400 W422 K428 F705 N11 W12 Y13 R31 R64 R243 R292 R316 G337 F338 Y340 G357 W379 K385 F653
External links
PDB RCSB:5h3u, PDBe:5h3u, PDBj:5h3u
PDBsum5h3u
PubMed27834343
UniProtQ8TEQ6|GEMI5_HUMAN Gem-associated protein 5 (Gene Name=GEMIN5)

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