Structure of PDB 5h3r Chain A

Receptor sequence
>5h3rA (length=141) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
TSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAA
CITPVELKKVLSVDLGALTRMLDRLVSKGWVERLPNPNDKRGVLVKLTTG
GAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP
3D structure
PDB5h3r Structural characterization of the DNA-binding mechanism underlying the copper(II)-sensing MarR transcriptional regulator.
ChainA
Resolution2.67 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T39 Q42 D67 A70 R73 M74 R77 K93 R94 T36 Q39 D64 A67 R70 M71 R74 K90 R91
BS02 dna A P57 V58 L68 G69 T72 R73 R86 R94 G95 V96 P54 V55 L65 G66 T69 R70 R83 R91 G92 V93
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006950 response to stress
GO:0009408 response to heat
GO:0045892 negative regulation of DNA-templated transcription
GO:0046677 response to antibiotic
GO:0071236 cellular response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:5h3r, PDBe:5h3r, PDBj:5h3r
PDBsum5h3r
PubMed28124121
UniProtP27245|MARR_ECOLI Multiple antibiotic resistance protein MarR (Gene Name=marR)

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