Structure of PDB 5h1k Chain A

Receptor sequence
>5h1kA (length=674) Species: 9606 (Homo sapiens) [Search protein sequence]
QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTP
PFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVV
TEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPR
TIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIA
WCPLPGEDCLSIGCYLATGSKDQTIRIWSCSRGRGVMILKLPFKERLWLT
LHWPSNQPTQLVSSCFGGELLQWDLTQKYTLFSASSEGQNHSRIVFNLCP
LQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDI
GSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCL
AFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLPSLAL
YSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADG
KIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSY
LMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWS
PHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCI
YSGADDFCVHKWLTSMQDHSRPPQ
3D structure
PDB5h1k Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A N13 W14 Y15 R33 R66 R284 R335 G380 F381 Y383 W422 K428 E556 K579 L580 N605 Y660 N11 W12 Y13 R31 R64 R246 R293 G338 F339 Y341 W380 K386 E508 K531 L532 N557 Y612 PDBbind-CN: Kd=0.24uM
External links
PDB RCSB:5h1k, PDBe:5h1k, PDBj:5h1k
PDBsum5h1k
PubMed27881601
UniProtQ8TEQ6|GEMI5_HUMAN Gem-associated protein 5 (Gene Name=GEMIN5)

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