Structure of PDB 5h1e Chain A

Receptor sequence
>5h1eA (length=239) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDM
SWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLM
AICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMI
QKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFG
3D structure
PDB5h1e SRC2-3 binds to vitamin D receptor with high sensitivity and strong affinity
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 S252 I256 L259 E416 I58 K62 S72 I76 L79 E236
BS02 VDX A Y143 L229 S233 R270 S271 S274 W282 V296 H301 H393 Y21 L49 S53 R90 S91 S94 W102 V116 H121 H213 BindingDB: Ki=0.1nM,EC50=0.2nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5h1e, PDBe:5h1e, PDBj:5h1e
PDBsum5h1e
PubMed27890450
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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