Structure of PDB 5gzb Chain A

Receptor sequence
>5gzbA (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
VWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGK
TRTRKQVSSHIQVLARRKAREIQAKLKDQAAKDKALQSMAA
3D structure
PDB5gzb DNA-binding mechanism of the Hippo pathway transcription factor TEAD4
ChainA
Resolution2.704 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A L68 Q97 S100 R108 R111 L27 Q56 S59 R67 R70 PDBbind-CN: Kd=0.23uM
BS02 dna A K65 I66 M74 G76 N78 E79 R95 K96 Q103 K24 I25 M33 G35 N37 E38 R54 K55 Q62 PDBbind-CN: Kd=0.23uM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5gzb, PDBe:5gzb, PDBj:5gzb
PDBsum5gzb
PubMed28368398
UniProtQ15561|TEAD4_HUMAN Transcriptional enhancer factor TEF-3 (Gene Name=TEAD4)

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