Structure of PDB 5gt4 Chain A

Receptor sequence
>5gt4A (length=255) Species: 9606 (Homo sapiens) [Search protein sequence]
DSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSVT
LELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAI
EVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQV
GLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIR
CRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLV
LEVFG
3D structure
PDB5gt4 Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R,5Z,7E,14beta,17alpha)-2-cyanopropoxy-9,10-secocholesta-5,7,10-triene-1,3,25-triol
ChainA
Resolution1.83 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2KB A Y143 D144 Y147 F150 L233 S237 I271 R274 S275 S278 W286 H305 H397 Y26 D27 Y30 F33 L65 S69 I103 R106 S107 S110 W118 H137 H229
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5gt4, PDBe:5gt4, PDBj:5gt4
PDBsum5gt4
PubMed
UniProtP11473|VDR_HUMAN Vitamin D3 receptor (Gene Name=VDR)

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